NeuroBreath

Depression — Tools, Management & Recovery

Comprehensive, evidence-based tools and resources for managing depression. Track your progress, access treatment information, and find support.

Understanding Depression

280M+
People globally affected by depression
16%
UK adults with moderate-severe symptoms (2023)
13.1%
US population aged 12+ with depression
Treatable
With evidence-based interventions

What is Depression?

Clinical Depression (MDD)

Major Depressive Disorder is more than sadness—it's a persistent condition lasting at least two weeks with five or more symptoms including depressed mood, loss of interest, changes in sleep/appetite, fatigue, difficulty concentrating, and feelings of worthlessness.

The Neurobiology

Depression involves complex interactions between neurotransmitters (serotonin, dopamine, norepinephrine), HPA axis dysregulation leading to elevated cortisol, and chronic neuroinflammation affecting brain regions like the hippocampus and prefrontal cortex.

Types of Depression

  • • Major Depression (MDD): Severe episode lasting 2+ weeks
  • • Persistent Depression (PDD): Chronic, lasting 2+ years
  • • Seasonal (SAD): Pattern linked to seasons
  • • Postpartum: During/after pregnancy

Depression vs. Sadness

Normal sadness is temporary and situational. Depression is persistent, pervasive, significantly impairs functioning, and involves physical symptoms. It's a medical condition requiring professional treatment—not a character flaw or weakness.

Interactive Wellness Tools

Evidence-based tools to help manage symptoms, track progress, and build recovery skills.

Behavioral Activation

Taking action, even small steps, is one of the most effective ways to break the cycle of depression

The 1-3-5 Framework

Behavioral Activation (BA) is an evidence-based component of Cognitive Behavioral Therapy. The principle is simple: action precedes motivation. By scheduling and engaging in activities, particularly those aligned with your values, you can gradually improve mood and energy.

Use this daily framework to structure achievable goals: 1 big thing, 3 medium tasks, and 5 small wins. Start small and celebrate progress.

1 Big Thing

One important task that moves you forward

3 Medium Tasks

Three meaningful activities

5 Small Wins

Five simple, achievable actions

Tips for Success

Start small: Even one task is progress

Schedule activities: Plan them like appointments

Include pleasurable activities: Not just obligations

Track your mood: Notice how activities affect you

Evidence-Based Treatment & Management

Comprehensive information on treatment options, lifestyle interventions, and recovery strategies

Crisis Resources

Free, confidential support available 24/7

Emergency

If you're in immediate danger, call emergency services:

🇬🇧 UK: 999

🇺🇸 US: 911

🇬🇧 UK Crisis Support

Samaritans

116 123 (24/7)

Crisis Text (Shout)

Text SHOUT to 85258

NHS 111

Dial 111 or 111.nhs.uk

🇺🇸 US Crisis Support

988 Suicide & Crisis Lifeline

Dial 988 (24/7)

Crisis Text Line

Text HELLO to 741741

NAMI Helpline

1-800-950-6264

This platform provides educational information and self-help tools. It is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified mental health provider with any questions regarding a medical condition.

Content based on evidence from NHS, NICE, WHO, DSM-5-TR, APA, NIMH, and peer-reviewed research (2026).